PSC – Primary Sclerosing Cholangitis
Primary sclerosing cholangitis is a health condition that affects the bile ducts, which are responsible for transporting bile from the liver to the small intestine. Bile is a fluid involved in digestion, and when a person develops primary sclerosing cholangitis, they have inflammation that leads to scarring in the bile ducts.

Over time, scars in the bile ducts cause them to become hard and narrow, slowly leading to liver damage as the disease progresses. Disease progression is typically slow with primary sclerosing cholangitis, so people who have the condition may generally feel pretty well in the early stages. That being said, disease progression can vary between people.
Common Symptoms
- “I felt tired all the time, and I experienced itching all over my body.”
- “As my condition got worse, I started to have pain in the upper right area of my abdomen, as well as frequent fevers and night sweats.”
- “I started to lose weight, and I had yellowing in my skin and eyes.”